Psalm 22:1 (ESV) — 1 My God, my God, why have you forsaken me? Why are you so far from saving me, from the words of my groaning?

Matthew 27:46  has Jesus taking these words as His own upon the cross.

Once more His substitutionary work – His acting in OUR place takes center stage. For, these are the words mankind ought to have been crying out to God all along. But we did not perceive how our sin had separated us from Him. In our darkness and hardness, we thought there was but a minor rift if at all. Our own sense of the uncrossable chasm placed between God and ourselves due to our sin had little impact upon us. We have been so fallen for so long, that we have come to see the pain and sorrow of this present age is just the natural order of things. We do not take in the fact that every ache and pain, every sorrow and grief, every disaster, natural and man-made – every tragedy and crime, every atrocity of man screams out to us that something is horribly, horribly wrong. But it did not escape our great Substitute. He fully grasped our dire estate. He groaned out what we were too dull to comprehend. He appeals to the God of Heaven on our behalf. He bids Him to take notice of our dread condition. And He was heard. He uttered these words on the Cross – even as His own blood was atoning for the sin that put Him there.

What a marvelous Savior He is.